MAS1 oncogene


The MAS1 oncogene is a G protein-coupled receptor, which binds the angiotensin-II metabolite Angiotensin. The MAS1 receptor when activated by binding angiotensin- opposes many of the effects of angiotensin-II activated angiotensin receptor. Hence MAS1 receptor agonists have similar therapeutic effects as angiotensin-II receptor antagonists including lowering blood pressure.