An agent code-named "Tiger" India's top spy and an officer of the Research and Analysis Wing is conducting a mission in northern Iraq. Tiger is forced to kill one of his own men who has defected to Pakistan's spy agency Inter-Services Intelligence. He subsequently kills many ISI agents in his escape from Iraq. Tiger returns to India and reports to his boss, Shenoy, in New Delhi. He is immediately sent on a mission to Dublin to observe a scientist of Indian origin, Professor Anwar Jamaal Kidwai, who teaches at Trinity College and is suspected of sharing his findings with the Pakistani defence establishment. Fellow RAW agent Gopi accompanies Tiger on this mission. Tiger meets the scientist but fails to spend enough time for his observance and instead begins to spend time with the scientist's caretaker Zoya, who is studying at a local dance academy. He tries to befriend Zoya to extract information, but begins to discover his human side as he grows closer to her. Tiger is attacked and robbed at his residence by a person suspected to be an ISI agent. Gopi repeatedly warns Tiger not to fall in love with Zoya, but his love cannot be stopped. Tiger asks Zoya for a date and there they both came to know about their feelings for each other. Before telling her his feelings, during a visit to dance academy, Tiger discovers that Zoya is an ISI agent and refuses to commit treason on Pakistan when he asks. Instead of killing Zoya, Tiger lets her go. Some time later, Tiger and Zoya meet again at a UN Foreign Minister's Meeting in Istanbul when Zoya signals to him using a cryptic message. They decide to leave everything for their love and fool their respective agencies by taking a flight to Cuba, having told their agencies that they are in Kazakhstan. Some years later, their agencies trace Zoya and Tiger due to a CCTV recording. They track them down in Havana, Cuba, and the ISI agents catch Zoya. Tiger meets Gopi, who is searching for him for RAW, and having lied to Gopi that both Tiger and Zoya intend to return to India and cooperate with RAW, convinces Gopi to save Zoya from the ISI agents. Instead of returning to India, the pair trick Gopi and escape aboarding an aeroplane. Tiger calls Shenoy, who tells him that RAW will find both spies. Tiger tells Shenoy that they will only return when Pakistan and India no longer need ISI and RAW. In the epilogue, several images of Tiger and Zoya in cities including Venice, Cape Town, Zurich and London are shown, where sightings of them have been reported. But neither agencies could catch them.
''Tiger Zinda Hai'' (2017)
A sequel titled Tiger Zinda Hai was announced on 13 September 2016. Salman Khan and Katrina Kaif reprise their roles from the first film. In this film, Tiger is presumed to be dead by both the agencies, but it turns out that he is alive and fighting by himself against a global terror organization. This sequel is based on the 2014 abduction of Indian nurses by ISIL. Indian agent Tiger and Pakistani agent Zoya join forces in the name of humanity, against the militant messiah Abu Usman. Tiger Zinda Hai is an espionage action drama that follows a daring rescue mission in Iraq.
A grapc titled Ek Tha Tiger: Mahasagar Ki Suraksha was published in 2012 by Yomics. Post release, the comic failed to generate a positive word-of-mouth. Joginder Tuteja of Bollywood Hungama commended the comics' design but said that the main story failed to meet his expectations of a deeper plot, exciting narrative and a tighter script.
Another graphic novel named Ek Tha Tiger: Caught In The Web has been published in 2012 by Yomics, which also features some Hum Tum characters.
Games
An android game base on the 2012 film has been released on the same year.
Another game based on the 2012 film has been released on the same year, which is a Windows version game published by skf.
