Lichter has authored or co-authored fourteen books and over a hundred scholarly articles and monographs on the news and entertainment media. His best-known work, The Media Elite, argued that journalists, on average, held more liberal political views than the general public, and that their backgrounds and outlooks affect their coverage of the news. This claim was extended by conservative pundits as evidence for a liberal bias in the media. It also provoked widespread debate among journalists and their critics. The Media Elite was based on interviews with major media journalists and content analysis of their work. Lichter and his co-authors have also written on the social and political perspectives of popular culture, in books such as Prime Time and Watching America, as well as on news coverage of science and health issues, in Environmental Cancer—A Political Disease and It Ain't Necessarily So. His most recent books are The Nightly News Nightmare: Television Coverage of Presidential Elections ; and The Mediated Presidency: Television News and Presidential Governance. These works use content analysis to examine the media's coverage of government and election campaigns. In 1986 Lichter and his late ex-wife, sociologist Linda Lichter, established the Center for Media and Public Affairs, a non-profit organization that sought to influence public debate on the media by publishing frequent studies of media coverage using the social scientific tool of content analysis. This was the first time this type of academic research was used on a regular and systematic basis to affect the general public's view of the media. Since then other groups have followed suit, including the Annenberg School for Communication and the Pew Foundation's Project for Excellence in Journalism. In 2004 the CMPA became affiliated with the George Mason University.
Some critics, such as Fairness and Accuracy in Reporting and the Columbia Journalism Review, have criticized Lichter and the CMPA for holding a conservative bias of their own or for being funded by conservative foundations. Nonetheless, major media outlets regularly carry stories based on the CMPA's studies, and the organization was described by the Los Angeles Times' Tom Rosenstiel as "non-partisan" in an interview in the D.C.-based City Paper. USA Today also described Lichter's methodology as "non-partisan", and Newsday characterized his research as "non-ideological." After a Washington Post article referred to CMPA as "conservative," the Post published a "Clarification", which concluded, "The center describes itself as nonpartisan, and its studies have been cited by both conservative and liberal commentators."