RIPK3
Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the RIPK3 gene.
The product of this gene is a member of the receptor-interacting protein family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Interactions
RIPK3 has been shown to interact with RIPK1 to form an amyloid spine
