Joséphine Caroline married her maternal first cousinPrince Karl Anton of Hohenzollern-Sigmaringen on 28 May 1894 in Brussels. He was the youngest son of her mother's oldest brother. Their relationship was described as a happy one. They lived in Namedy Castle on the Rhine which they had purchased in 1909. During World War I, she made her home a military hospital for wounded soldiers while her husband served as a Prussian lieutenant general. Exhausted from years of warfare, he died shortly after his return to Namedy in 1919, at age 51. In 1936, Joséphine Caroline entered a Benedictine convent in Namur, taking the name of Sister Marie-Josephine, and remained a nun for the rest of her life. She is buried in the Couvent des Soeurs de Notre-Dame in Namur.
Princess Stephanie Josephine Karola Philippine Leopoldine Marie of Hohenzollern she married Joseph Ernst, Count of Glött on 18 May 1920 and they were divorced on 25 May 1943.
Princess Marie Antoinette Wilhelmine Auguste Viktoria of Hohenzollern she married Baron Egon Eyrl von und zu Waldgries und Liebenaich on 27 November 1924. They had four children:
*Baroness Veronika Eyrl von und zu Waldgries und Liebenaich she died at the age of fifteen.
*Baroness Stephanie Eyrl von und zu Waldgries und Liebenaich she married Josef von Zallinger-Stillendorf on 27 November 1950. They have four children.
*Baroness Elisabeth Eyrl von und zu Waldgries und Liebenaich she married Bernhard Baron von Hohenbuhel gennant Heufler of Rasen on 9 August 1954. They have six children.
*Baron Carl Josef Eyrl von und zu Waldgries und Liebenaich he married Countess Isabelle Ceschi a Santa Croce on 12 April 1975. They have four children.
Prince Albrecht Ludwig Leopold Tassilo of Hohenzollern he married Ilse Margot von Friedeburg on 19 May 1921. They had five children:
*Princess Josephine Wilhelma of Hohenzollern-Sigmaringen
*Princess Luise-Dorothea of Hohenzollern-Sigmaringen she married Egbert Count of Plettenberg on 11 June 1947. They have seven children.
*Princess Rose-Margarethe of Hohenzollern-Sigmaringen she married Edgar Pfersdorf on 15 September 1955. They have four children.
*Princess Maria of Hohenzollern-Sigmaringen she died at one day old.
*Prince Godehard-Friedrich of Hohenzollern-Sigmaringen he married Heide Hansen on 29 August 1971. They have two children.
Princess Henriette Leopoldine Wilhelmine of Hohenzollern-Sigmaringen she died at four days old.
28 May 1894 – 6 January 1958: Her Royal Highness Princess Karl Anton of Hohenzollern, Princess of Belgium, Princess of Saxe-Coburg and Gotha, Duchess of Saxony
