Polypeptide N-acetylgalactosaminyltransferase enzymology , a polypeptide N-acetylgalactosaminyltransferaseenzyme that catalyzes the chemical reaction substrates of this enzyme are UDP-N-acetyl-D-galactosamine and polypeptide, whereas its two products are UDP and N-acetyl-D-galactosaminyl-polypeptide .belongs to the family of glycosyltransferases , specifically the hexosyltransferases . This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1 . It has 2 cofactors: manganese , and calcium .Nomenclature The systematic name of this enzyme class is UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase . Other names in common use include: protein-UDP acetylgalactosaminyltransferase, UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase , UDP-N-acetylgalactosamine:kappa-casein polypeptide, N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-glycoprotein, acetylgalactosaminyltransferase, glycoprotein acetylgalactosaminyltransferase, polypeptide-N-acetylgalactosamine transferase, UDP-acetylgalactosamine-glycoprotein, acetylgalactosaminyltransferase, UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, UDP-N-acetyl-alpha-D-galactosamine:polypeptide, N-acetylgalactosaminyltransferase, UDP-N-acetylgalactosamine-glycoprotein, N-acetylgalactosaminyltransferase, UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase, UDP-N-acetylgalactosamine:polypeptide, N-acetylgalactosaminyltransferase, and UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase.
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