Nine Partners Creek begins in a small unnamed pond on a hill in New Milford Township. It flows east-northeast for a few tenths of a mile before passing through Hunt Lake, and then turns south. After a few tenths of a mile, the creek turns southeast for more than a mile, entering Harford Township. Here, it turns south-southeast for several tenths of a mile before beginning to flow south alongside Interstate 81, crossing Pennsylvania Route 547 and receiving the tributary Leslie Creek from the. After a few miles, it flows south-southeast for more than a mile before turning south again. Several tenths of a mile further downstream, the creek receives the tributary Butler Creek from the and enters Lenox Township. Here, it continues flowing south for several tenths of a mile before turning south-southeast. Several tenths of a mile further downstream, the creek crosses Pennsylvania Route 92 and reaches its confluence with Tunkhannock Creek. Nine Partners Creek is approximately long. The creek joins Tunkhannock Creek upstream of its mouth.
Tributaries
Nine Partners Creek has two named tributaries: Butler Creek and Leslie Creek. Butler Creek joins Nine Partners Creek upstream of its mouth, within of Harding Corners, and drains an area of. Leslie Creek joins Nine Partners Creek upstream of its mouth, within of Lenox, and drains an area of.
Geography and geology
The elevation near the mouth of Nine Partners Creek is above sea level. The elevation near the creek's source is above sea level. The surficial geology inside the valley of Nine Partners Creek in its lower reaches mainly consists of alluvium and fill, although there is a small patch of alluvial fan. The sides of the valley have surficial geology containing a till known as Wisconsinan Till and bedrock consisting ofsandstone and shale. Further upstream the surficial geology is similar, but with two more alluvial fan patches and a wetland patch. Along the uppermost reaches of the creek, includes Wisconsinan Till and alluvium, as well as small patches of alluvial fan and wetland. Nine Partners Creek has been described as a "small creek". Some sources describe the creek as flowing into Leslie Creek, which is one of its tributaries.
Watershed
The watershed of Nine Partners Creek has an area of. The mouth of the creek is in the United States Geological Survey quadrangle of Lenoxville. However, its source is in the quadrangle of Harford. The creek's mouth is located near East Lenox. A natural lake known as Hunt Lake is located in Nine Partners Creek. It has an area of and is located in New Milford Township. Other lakes in the creek's watershed, on tributaries of the creek, include the Tyler Lake and the Tingley Lake. Interstate 81 is located in the vicinity of Nine Partners Creek. The reach of the highway running in the creek's vicinity was built in the 1960s.
The drainage basin of Nine Partners Creek is designated as a Coldwater Fishery and a Migratory Fishery. In 2005, one of a number of brook trout released into Tunkhannock Creek to study trout movement made its way downstream to go up Nine Partners Creek as far as the tributary Butler Creek. This was the only occurrence of a trout entering a tributary stream during the study. Fishing can be done in the creek. In the upper part of the Nine Partners Creek watershed, 65.4 percent of the watersheds have a Habitat Quality Index of at least 0.50.