Nayyem was born in Kabul in 1981 and lived in an elite district near Hafizullah Amin's palace. In 1984, ten days after his younger brother Masi Nayyem was born, their mother died. He has stated that he is a Pashtun and "Muslim by birth". His native tongue is Dari which is similar to Persian. In Afghanistan, his father, Muhammad Haim, had been Minister of Education and was responsible for the construction of educational facilities before the USSR invasion of Afghanistan in December 1979. After the Soviet invasion, his father did not want to work for the Soviets and quit his post. In 1987 and because of the destruction of the ongoing Soviet Union's War in Afghanistan, his father went to Moscow to study and met Ukrainian Valentina Kolechko whom he later married in early 1989. Mustafa Nayyem became fluent in Russian and Ukrainian after he moved with his father to Moscow in August 1989 living near the Nakhimovsky Prospektmetro station and later to Kyiv in 1990 attending 61st school near the :uk:Лук'янівська площа|Lukyanivsky market. Nayyem graduated from the Technical Lyceum in Kiev in 1998, and the Aerospace Systems Department of Kyiv Polytechnic Institute in 2004. He speaks fluent Ukrainian, Pashto, Russian, and English. He and Anastasia Ivanova who is from Lviv and was a photographer for :uk:Коммерсантъ Украина|Kommersant-Ukraine, have a son, Mark-Mikhei, and both mother and son are Jewish. His brother Masi Nayem is a lawyer and, in April 2016, deployed as a Ukrainian paratrooper to the Donbass - Avdeevsky industrial zone which was the hottest point of war during the Russian invasion of Ukraine.
Career
Journalism
Nayyem worked as a reporter for the :uk:Коммерсантъ Украина|Kommersant-Ukrainy newspaper from 2005 to 2007, and then for Shuster LIVE, a political talk show on Ukrainian television, from 2007 to 2011. In 2009, Nayyem received national attention following Ukrayina TV channel's live discussion with then-presidential candidate Viktor Yanukovych. During the discussion, he questioned Yanukovych about the latter's acquisition of the Mezhyhirya Residence. In 2010, Nayem was briefly detained by police officers, reportedly as a result of racial profiling for "persons of Caucasian appearance". The following day, Nayem wrote an article in which described the events that led to his detention. He stated, "Xenophobia should not become the face of Ukrainian nationality" and requested the firing of one of the officers responsible. Nayyem frequently contributes news and articles to Ukrayinska Pravda. From September 2011 to late April 2013, he worked for the Ukrainian television channel TVi. After resigning due to a conflict with the channel's new management, he started a web project together with colleagues who also left the channel. Their project was named Hromadske.TV.
Activism
Using Facebook, Nayem was one of the first activists to urge Ukrainians to gather on Independence Square in Kiev to protest Viktor Yanukovych's decision to "pause" preparations for signing an association agreement with the European Union. His post on Facebook on November 21, 2013, was a summons to rally for the Euromaidan protests which led to the overthrow of the Yanukovych government.
Ukrainian entertaining group "Kvartal 95" mentioned Nayyem in their song about Ihor Kolomoyskyi and their meeting in relation to the "Ukrnafta issue" that surfaced in the Ukrainian media soon after Euromaidan events.