The assumed course of study follows the Smart Core curriculum developed by the Arkansas Department of Education, which requires 22 units to graduate and is supplemented by the school's career academies model and Advanced Placement courses and exams. The Mountain Home High School is accredited by the ADE and has been accredited by AdvancED since 1955.
Career academies
Mountain Home High School operates using the academies model. Students are divided into academies based on their interests and learning styles. Each academy consists of core classes and elective classes unique to each academy. Students may choose electives from other academies, but are encouraged to follow a "completer" path within their own academy. Teachers are also split into academies, theoretically according to their strengths.
Extracurricular activities
The Mountain Home High School mascot is the Bomber with blue and gold serving as its school colors.
Athletics
The Mountain Home Bombers participate in interscholastic activities in the 6A Classification administered by the Arkansas Activities Association. The Bombers compete in the 7A/6A East Conference in sports such as: football, baseball, basketball, bowling, competitive cheer, cross country, competitive dance, golf, soccer, softball, swimming, tennis, track and field, volleyball, and wrestling.
Cross Country: The boys cross country team won a state cross country championship in 2000 and 2020. The Lady Bomber teams won three consecutive state championships. The teams also completed a sweep of the state championships in 2012 while the girls won another trophy in 2011
Golf: The boys golf team won a state golf championship title in 2007.
Basketball: The Bombers boys basketball team won its only state basketball championship in 1966. The Lady Bombers were state champions in 1986.
Softball: The Lady Bombers won a state fastpitch softball championship in 2008 and 2010.
The institution was awarded an American Forest & Paper Association Recycling Award. During the 2004–05 school year, Mountain Home High School students collected more than 6 tons of paper for recycling, and created a model program to promote natural resource conservation. The Mountain Home High School Band marched in the Macy's Thanksgiving Day Parade, 2006. Mountain Home High School, technically the Mountain Home Career Academies, received high honors as being the recipient of the Ford Fund for its efforts in career academies and complete integration of all three core career academies. The ACME and HHS academies were given a national award of distinction for their efforts.