Mike & Molly

Cast

• Billy Gardell as Officer Michael "Mike" Biggs, a Chicago police officer attempting to lose weight. He doesn't appear to be a deep thinker, but he's good-hearted and humorous. He often caves in to his mother's demands, much to Molly's dismay, but his relationship with Molly has made him much more independent.
• Melissa McCarthy as Molly Flynn, a fourth-grade teacher at Walter Payton Elementary School, also attempting to lose weight. She is sweet, happy, intelligent, and caring. She is the rational member of her family, but is known to have a quick temper and has built up much debt from lavish shopping and traveling. When she and Mike finally marry, she keeps Flynn as her last name, and they spend much of their time trying to get pregnant. She quits her teaching job in Season 4 to become a writer.
• Reno Wilson as Officer Carlton "Carl" McMillan, a Chicago police officer and Mike's partner and best friend. He tends towards self-pity, owing to his mother abandoning him. He lived with his grandmother for a long time until she made him move into his own apartment. He struggles in relationships with women and is depicted as lonely. He is a big fan of soul and gospel music and openly dislikes bluegrass. In Season 2 he had a steady relationship with Christina, a single mother with a young son, but in Season 3 Christina broke up with Carl to try to work things out with James, her famous football player ex-husband and her son's father. He began a relationship with Victoria at the end of Season 4, but by the end of Season 5, it was over until they got back together in the series finale.
• Katy Mixon as Victoria Flynn, Molly's dimwitted, kindhearted, party-girl sister who is often high on marijuana and sleeping around with multiple men. She is employed as a funeral home beautician. At the end of Season 4 she began a relationship with Carl which ended badly in Season 5 but they got back together in the series finale.
• Swoosie Kurtz as Joyce Flynn-Moranto, mother of Molly and Victoria. Widowed when her daughters were young, she began dating Vincent Moranto in Season 1. She is very modern and attempts to stay youthful; she also drinks heavily and has a hair-trigger temper. As of the Season 3 episode "Thanksgiving Is Cancelled", she is married to Vincent.
• Nyambi Nyambi as Babatunde, aka Samuel, a sarcastic waiter at Abe's, the restaurant where Mike and Carl eat. He is also a close friend to Mike, Carl, and eventually Molly. He is from Senegal and often refers to the suffering in his home country, so he cannot easily sympathize with his restaurant patrons' "petty" problems. He and Carl became roommates in Season 3. In Season 5, Samuel's real name is revealed to be Babatunde when he becomes the new owner of Abe's Diner, since renamed Abe's Hot Beef.
• Louis Mustillo as Vincent "Vince" Moranto, Joyce's on/off boyfriend, then fiancé, now husband and Molly and Victoria's stepfather, and Mike's stepfather-in-law. A widower, he tends to be flirty, chauvinistic, and sarcastic. A high-school dropout, he's not the most intelligent, but he cares deeply for Joyce and has shown fatherly care toward Molly and Victoria—despite having met Molly after being set up on a blind date with her, and his constant comments about Victoria's breasts. He once married a much older, very unpleasant woman from whom he fled after borrowing $2,000; he didn't officially end this marriage until the truth came out and Joyce kicked him out of her house until Mike convinced the "wife" to sign divorce papers.
• Rondi Reed as Margaret "Peggy" Biggs, Mike's mother. She is very controlling and traditional, as well as grumpy and cranky. She often refers to her ex-husband Jack leaving her and running away to Florida with a prostitute. Peggy is also very fussy over her dog Jim, whom she treats more like a son than a pet. In Season 2, Peggy began working as a lunch lady at the elementary school where Molly teaches. In Season 3, she dates a police captain who is Mike's supervisor, but Peggy breaks things off during the season finale.
• Cleo King as Rosetta McMillan, Carl's grandmother. She is very traditional and has professed deep love for her grandson, but is outwardly annoyed by Carl's behavior and made him move out in Season 3, saying she still loves him and looks forward to him visiting but wants him to finally become a responsible adult on his own. She has a big heart and treats Mike, who calls her "Nana", like a second grandson. She often gives Mike and Carl advice. She once recalled that when Carl was young, he could quote the entire speech of Martin Luther King, Jr. as well as every episode of The Dukes of Hazzard.
• David Anthony Higgins as Harry, a friend of Mike and Molly's who attends the same Overeaters Anonymous meetings. He is nice but socially awkward and tends to say whatever he is thinking, even thoughts that make him seem pathetic. He was shown to have an almost obsessive crush on Victoria; when she finally kissed him in season 3, he realized that he is gay.
• Suzie Q as Jim, Peggy's dog, it is a Griffon Bruxellois mixed with a Chihuahua.

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