In 1979, Bramlett, a former Democrat, sought the Republican nomination for governor but lost in the low-turnout primary election to Gil Carmichael, a businessman from Meridian, 17,216 to 15,236. Carmichael had been the 1975 nominee against Cliff Finch and had also carried the GOP banner against U.S. Senator James Eastland in 1972. Also in the race was a persistent Eastland critic, the Republican-turned-Independent Prentiss Walker, a former member of the United States House of Representatives for Mississippi's 4th congressional district. In 1983, Bramlett won the gubernatorial primary and faced the Democrat Bill Allain, a popular state attorney general known for his fight against utility rate hikes and his opposition to the storage of nuclear waste in Mississippi. In the campaign, the private detective Rex Armistead, formerly with the Mississippi State Sovereignty Commission, helped to spread rumors that Allain had sexual intercourse with two African-American male transvestites. Allain denied the charges. The transvestites went on the record with a lie detector test but in 1984, after the election had been held, they claimed that they had never met Allain and had been paid for their testimony. Bramlett lost the general election, 288,764 to Allain's 409,209. Charles Evers, the African American civil rights activist from Fayette, ran as an Independent and polled 30,593. Carmichael ran in 1983 for lieutenant governor against the incumbent Democrat Brad Dye, who prevailed with 464,080 votes to Carmichael's 257,623. Bramlett hence outpolled Carmichael by just over 31,000 votes when both were on the ballot as ticket mates. Bramlett also served as the in-state representative for Republican U.S. Senator Thad Cochran, first elected to the U.S. House in 1972 and the Senate in 1978.
Family life
In 1947, Bramlett married the former Virginia McGehee, known as Skeeter Bramlett, a native of Greenville, Mississippi, and the daughter of Mr. and Mrs. William Thomas McGehee. Virginia attended elementary school in Grenada, Mississippi, and returned to Greenville to graduate there from Greenville High School. She subsequently received a degree from Randolph-Macon Women's College, now known as Randolph College in Lynchburg, Virginia, where she was a member of Chi Omegasorority and the president of the Student Government Association. She was named "Miss Greenville" by the Chamber of Commerce. When the Bramletts married, he was serving in the Marines, and the young couple lived for a time in Quantico, Virginia, and Washington, D.C. They then returned to Clarksdale, where Bramlett had his farming interests. They were active in the First Presbyterian Church, a conservativePresbyterian Church of America congregation in Clarksdale. Three children were born to the union of Leon and Virginia Bramlett: Leon C. Bramlett, III, of Clarksdale, Sallie Key Bramlett Russell, and Virginia Hartridge Bramlett of Bowie in Montague County near Wichita Falls, Texas. Leon, Jr., and Virginia Bramlett, Sallie Russell, and Leon Bramlett, Sr., are interred at Oakridge Cemetery in Clarksdale. Bramlett was the owner of Bramlett Farms and Bramlett Gin & Delint in Clarksdale. He died on October 19, 2015.