The main characters are three best friends — Adam, Bruno and Cameron — who live and work inMelbourne. Adam is newly single, having come out of a long-term relationship, and is dealing with the dating world for the first time in a long time. Cameron is the sexual predator of the group, although this role has been somewhat lessened by the fact that his ex-wife Zoe — who left when he had an affair — is now part of the group, and is becoming friends with the women he dates. Bruno is a nurse who has a habit of falling for women who don't care for him, while ignoring the many women who do. All three are discovering that, in their late twenties, they are still single and really have no idea about women whatsoever. In keeping with the show's distinctly Melbourne feel, iconic Melbourne rock bandDallas Crane recorded a cover of Come See Me, originally by The Pretty Things, for the show's theme tune. The cover can be found as a B-side to the band's Curiosity single
The series premiered in Australia on 6 June 2005 - although it premiered in New Zealand some two months earlier. It struggled to find an audience from the beginning, with an average Australian viewership of 750,000 weekly viewers. These low ratings occurred despite the show having Desperate Housewives as a lead in, which at the time was attracting over 2 million viewers a week. It was thought by critics that Last Man Standing appealed only to "inner city lefties", unlike past successful Australian dramas such as Blue Heelers and All Saints which have more widespread demographic appeal. Given that a full 22 episodes had been filmed before the series began airing, the Seven Network aired consistent repeats to allow the show to find an audience. Ratings didn't climb, however, and in early September, the network announced the show's cancellation. The series finale aired on 25 October. This episode ended in a cliffhanger, which - due to the show's cancellation - will remain unresolved. The series began its airing in the UK on the FX channel in early 2006. The series began its airing in Finland on the Sub channel in June 2007.