De Queiroz’s research has focused primarily on the phylogeny and evolutionary biology of squamate reptiles, including his Master’s research on the phylogeny of iguanine lizards and his Ph.D. research on the phylogeny of phrynosomatinesand lizards. He worked with his mentors Richard Estes and Richard Etheridge on the phylogeny of Squamata and Iguanidae, respectively, and with Jacques Gauthier on the phylogeny of Lepidosauromorpha. He conducted research, including several publications with Jonathan Losos, on the phylogeny and adaptive radiation of Anolis lizards.
Theoretical research
De Queiroz also has interests in theoretical and conceptual topics in systematic and evolutionary biology. He published an article early in his career on the relationship between the sequence of ontogenetic transformations and phylogenetic inference. Beginning in 1998, he published a series of articles proposing how to achieve a unified species concept and outlining several of its consequences. In collaboration with Jacques Gauthier and Philip Cantino, de Queiroz has published another series of articles proposing and defending an approach to biological nomenclature based on definitions that specify the meanings of taxon names in terms of clades and common ancestry as an alternative to traditional approaches that are based on taxonomic ranks. He is coauthor of a draft Phylogenetic Code of Biological Nomenclature with Cantino. De Queiroz has published several articles on the history and philosophy of biology, related primarily, but not exclusively, to his own theoretical and conceptual contributions. He published a paper early in his career proposing that the Darwinian Revolution in systematic biology was not a sudden event but rather an extended process that is not yet completed. He has examined Charles Darwin’s writings on species and argued that his own ideas about how to achieve a unified species concept represent the ongoing development of the evolutionary view of species articulated by Darwin. He has examined the class versus individual interpretations of species and clades in light of his work on phylogenetic definitions of taxon names, proposing that contrary to how those interpretations are commonly presented, they are not mutually exclusive, which suggests that the same is true of ostensive and intensional definitions. He has argued that the philosopher Karl Popper’s concept of degree of corroboration is analogous to the likelihood ratio of nested hypotheses and that in phylogenetics the probability of the evidence given the backgroundknowledge in the absence of the hypothesis of interest is represented by the likelihood of a star tree.