On 15 October 1969, while paying a visit to the northern town of Las Anod, Somalia's then President Abdirashid Ali Shermarke was shot dead by one of his own bodyguards. His assassination was quickly followed by a military coup d'état on 21 October 1969, in which the Somali Army seized power without encountering armed opposition – essentially a bloodless takeover. The putsch was spearheaded by Major General Mohamed Siad Barre, who at the time commanded the army. The new Supreme Revolutionary Council that seized power subsequently named Mire as the Minister of Education in its first post-coup Cabinet. He resigned after nine months of his appointment to the office.
In 1978, a group of officials mainly from Mire's own Majeerteen clan, including Abdullahi Yusuf Ahmed, participated in an abortive attempt to overthrow Barre's dictatorial administration. Most of the people who had helped plot the coup were summarily executed, but Ahmed and several other colonels managed to escape abroad. Later that year, in adjacent Ethiopia, Mire and Ahmed formed a rebel movement called the Somali Salvation Front, with Ahmed serving as Chairman. The organization was subsequently renamed the Somali Salvation Democratic Front in 1979. It was the first of several opposition groups dedicated to ousting Barre's regime by force. In 1986, following Ahmed's imprisonment a few months earlier by the Ethiopian authorities, Mire was elected as the SSDF's new Chairman. Under his direction, the organization adhered to a moderate policy demanding free elections and the removal of foreign military bases. In 1990, on the eve of the civil war in Somalia and the toppling of Barre's regime, Mire was among the signatories of a manifesto advocating national reconciliation. As a representative of the SSDF, Mire opposed any military rule. Other signatories of the document included Aden Abdullah Osman Daar, Somalia's first president, and around 100 additional Somali politicians.
Puntland
In 1998, Mire, Abdullahi Yusuf Ahmed and other prominent figures from northeastern Somalia, including the region's political elite, traditional elders, members of the business community, intellectuals and civil society representatives, established the autonomous Puntland State of Somalia. The constitutional conference in which the declaration was made was held in Garowe over a period of three months, with the aim of delivering services to the population, offering security, facilitating trade, and interacting with both domestic and international partners. Ahmed was subsequently elected as the state's first President.
Present
In August 2013, Mire was a guest speaker at the Fourth Annual Ohio Somali Graduation Program in Columbus, Ohio. The event brought together hundreds of students, parents, professionals and leaders to honor the state's Somali secondary and tertiary graduates. Former Prime Minister of SomaliaMohamed Abdullahi Mohamed served as a keynote speaker, with financial scholarships awarded to the most outstanding pupils.