George Tiernay Mirehouse was born in Easton in Gordano, Somerset, on 11 May 1863. He was the second son of Henry John and Anne, and was named for his maternal grandfather. He came from a clerical family; his father was the rector of St George's Church in the village, and both his grandfathers had been vicars; on the paternal side, of St George's also, and on the maternal side, of Stradbally, County Waterford near the southern coast of Ireland. He attended Westminster School, where he played for the school's cricket team, appearing for the side against both the Marylebone Cricket Club and Charterhouse School in 1880. He then went up to Jesus College, Cambridge University in 1882. He was not invited to play in the freshmen's trial match during his first year at Cambridge, but did feature in the senior's trial match the following season, 1884, in which he took one wicket. He was low in the pecking order to play for Cambridge that year; in another trial match between the "First Twelve" and the "Next Sixteen", Mirehouse appeared for the latter, again taking one wicket in the match. Despite this, Mirehouse made his first-class debut for the University a couple of weeks later, playing against the Gentlemen of England; a collection of the best amateur players in the country. Mirehouse was used as the second-change bowler for Cambridge, and took one wicket, that of Sandford Schultz. He featured again the following week, against a Marylebone Cricket Club and Ground side rated as relatively weak by . On a pitch ruined by rain, he bowled 24 overs without taking a wicket during a heavy defeat for Cambridge. He did not play again for Cambridge that year, but did go on to make his first appearances in county cricket for Somerset County Cricket Club. On his county debut, against Hampshire, Mirehouse took three wickets in the first innings and another in the second; his first innings record of three wickets for 33 runs was his best in first-class matches for Somerset. Mirehouse opened the bowling alongside E. W. Bastard against Kent, but bowled 28 overs in the match without taking a wicket, while against Lancashire, he took two wickets on a pitch described as "dead from recent rains and in favour of the bowlers." Mirehouse had some appearances of note for the Lansdown Cricket Club during 1884, taking four wickets against the touring Gentlemen of Philadelphia in July, and taking seven wickets against the Incogniti in August. He played seven first-class matches for the university, but did not appear in the Varsity Match against Oxford University. Mirehouse achieved his best performance in first-class cricket for Cambridge, claiming four wickets in the second innings for the university against CI Thornton's XI. He also appeared a number of times for both Somerset and the Marylebone Cricket Club.
Later life
Mirehouse emigrated to Turramurra, Sydney where he ran a sugar refinery. He suffered from ill-health, including an ulcer which affected him for some time, but this was later cured. In an effort to improve his health, he took a six-week break on the south coast of Australia. On his return, he voiced concerns about business matters, and a few days later on 5 March 1923, hanged himself from his bed with a sash cord. A letter Mirehouse started writing to a friend in Bristol lamented: "My sufferings the past six months have been beyond all expression." Despite his apparent business worries, Mirehouse had £4,300 of stocks and £165 cash invested with the Bank of Australasia. He had never married, and his estate was left to his cousin, and brother-in-law, Egerton Bagot Byrd Levett-Scrivener.