The city issued a curfew after protests resulted in vandalism of public property and statues and some protesters threw rocks at police and citizens. Additionally, several businesses and restaurants had glass windows busted. Two men wearing MAGA hats were assaulted. At one point, police in riot gear used tear gas to stall protesters. Protesters halted traffic on Interstate-26. The following day, a group of 200 protesters formed in Marion Square. One protester, identified as Gee Jordan, was arrested in Marion Square after praising police officers, having stated "I love each and every one of you. I am not your enemy. You are not my enemy." He was charged with "disobeying lawful order" and has since been released from jail on bond. Charleston Police Chief Luther Reynolds defended the arrest, stating that "We specifically asked for , numerous times, to disperse. We said if you don't, you will be arrested".
Columbia
On May 30, 2020, protesters marched from the South Carolina Statehouse to the city of Columbia police station. Several businesses and restaurants in the nearby business district were vandalized. Mayor Stephen K. Benjamin announced a mandatory 6 p.m. curfew for the city. Four police officers were injured, one critically. Later that night shots were fired at police, and the shooters were arrested. The officers did not return fire.
On June 4, over 1,000 protestors peacefully marched down S.C. 160 to protest George Floyd's killing and support Black Lives Matter.
Greenville
On May 30, two protests were held at Peace Center and Falls Park. Not affiliated with Black Lives Matter, the first event was attended by Mayor Knox White. About 300 people marched at the second protest, some arrests were made.
Myrtle Beach
Hundreds of protesters attended a rally downtown on the morning ofMay 31. Protesters initially blocked the entrance to the Myrtle Beach Police Station in what felt like a "standoff" but when officers joined in and the Chief addressed the crowd cheered. Mayor Brenda Bethune declared a civil emergency due to a "credible threat" against police related to the protest. A curfew was set to start at 7pm May 31.
North Charleston
On June 4, around 100 protesters marched from Park Circle down to East Montague Avenue to rally against police brutality.
Rock Hill
On May 30, a peaceful protest was held at Fountain Park.
Sumter
On May 30, a peaceful protest was held outside the Sumter Police Department to voice support for George Floyd.