GRIN2C


Glutamate receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene.

Function

N-methyl-D-aspartate receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 and 1 or more of the 4 NMDAR2 subunits: NMDAR2A, NMDAR2B, NMDAR2C, and NMDAR2D.

Interactions

GRIN2C has been shown to interact with DLG4 and DLG3.