Muzika was born in Prague, Czechoslovakia. After finishing his study at the Academy of Arts, Prague in 1924, he received a one-year scholarship from the French government for studying at École des Beaux-Arts. In Paris he also received private lessons from František Kupka at his atelier. In Paris he met Max Jacob, who took him to meet Léonce Rosenberg. On Sundays he had regular meetings with Joseph Bernard, where he also met Maillol and Bissière, with whom he exhibited at Salon d'Automne. In 1925, after he returned from Paris, his experiences with the work of Georges Braque and Pablo Picasso led Muzika to change his style of painting. In his final years, he suffered from cardiac disease. He died 1 November 1974 in his atelier, with his final, unfinished work, "Staircase" on the easel.
Paintings
First period (1918–1924)
At first Muzika was influenced by Bohumil Kubišta. His first paintings portrayed still lifes and architecture. He then shifted to a primitivist neoclassicism. He focused on pastoral scenes and everyday life.
Second period (1925–1936)
After Paris he radically revised his artistic poetics. Objects lost their material character. His painting style relaxed. He created a new pictorial reality that took the form of Lyrical Cubism. After 1930, Muzika involved surrealist elements in his process. The poetics of Muzika's pictures were influenced by the work of Giorgio de Chirico and Muzika's own experiences as a stage designer.
Third period (1936-about 1948)
Muzika reacted to the Spanish Civil War, the occupation of Czechoslovakia, and the brutality of war. Muzika's wartime period shows the torment and grief of this tragic time with allegorical pictures. His paintings with imaginary landscapes, dark atmospheres, and jarring metaphors created the feeling of dramatic tension and darkness of the time.
The post–war period
"During the post-war period František Muzika developed his own original poetics that, in close accord with the trends of contemporary international art, elaborated further the original orientation of his poetical vision of the world."
Final years (1948–1974)
Muzika's topic of his paintings was the fossilized world. Muzika erased the differences between the real and unreal, the microcosm and macrocosm. His works emphasized heavy symbolism.
Other work
In 1927 Muzika started to expand to other fields, such as stage design and book illustrations. He was an editor of cultural magazines. One example of his 107-stage designs is “Julietta” by Bohuslav Martinů in the Czech National Theater. In 1927 he started his work on the book Krásné Písmo, which was published in 1958 in Czechoslovakia and Schöne Schrift in 1965, in German. He also designed many posters; for example, he did a poster for Emil Filla's exhibition and for Prague Spring 1946 and 1947. His symbol from the poster is still the logo for Prague Spring International Music Festival today. He illustrated many books including Karel Čapek’s R.U.R. Muzika's pupils included Daniela Havlíčková and Eliška Konopiská.
Exhibitions
Muzika’s paintings and drawings are in many Czech and foreign galleries, as well as in the Centre Pompidou, Paris. Muzika had many exhibitions in Czechoslovakia, beginning in 1922.
International group exhibits
1948 – Biennale Venice
1964 – Biennale Venice
1968 – Obsessions et Visions, Gallery André François Petit, Paris
1969 – Surrealism in Europe, Baukunst Gallery, Cologne, Germany