He was born in Jerez de la Frontera, Cádiz, Spain, the son of Diego Pérez de Burgos and Beatriz Martínez de Tremal, belonging to a distinguished Andalusian family. He possibly did his studies in Seville, and arrival in the Río de La Plata from Cádiz in 1581. He lived in Asunción and settled in Buenos Aries in 1583, where he married Juana de Aguilar y Salvatierra, daughter of Leonor de Zamora and her first husband Andrés Gil, natives of Ronda. Burgos was the successor of Antón García Caro, in the position of notary of Buenos Aires. He served as notary public and of Cabildo until 1606, being replaced by Manuel Martin. In 1606, Burgos presented before the City Council, his title of Royal Notary of the Spanish Indies, signed on February 11, 1581 by the King Philip II of Spain. He had an active participation as a government notary in the Río de la Plata. In 1584 he officiated the notarial deed in the interrogation conducted by Conquistador Don Juan de Torres de Vera y Aragón, against three English pirates, who had been persecuted by the Charruas Indians in the territory of Santa Fe Province. One of these pirates was John Drake, the nephew of Francis Drake. Burgos belonged to the second contingent of settlers established in the city of Buenos Aires. He also living in the provinces of San Miguel de Tucumán, Santa Fe and Corrientes. In 1596, he was appointed by Juan Ramírez de Velasco, to exercise the position of Alcalde and Justicia Mayor of Corrientes. Francisco Pérez de Burgos also served as Mayor of Buenos Aires, and Captain in the Fuerte de Buenos Aires. In 1614 he was elected regidor and appointed as fiel ejecutor of Buenos Aires, being replaced in that position on July 21 of that year by Francisco García Romero, a politician born in Extremadura. He continued to serve as deputy of the City Council of Buenos Aires until 1616, and died in the same city on July 21, 1617. He also devoted himself to agriculture and took part in the hunting of cimarron cattle in the Province of Buenos Aires. In 1604 he received land grants in the Paraná River by Hernando Arias de Saavedra, governor of Buenos Aires. He was the owner of a farm located on the Riachuelo to the south of the city. The passage of Burgos today Puente Alsina, owes its name to Francisco Pérez de Burgos. During the British invasions of the Río de la Plata, the Burgos passage was crossed by the English troops to enter the city of Buenos Aires.
