He studied at the ETH Zurich and obtained a doctorate in 1878 under Robert Bunsen at Heidelberg University. Lippmann ran large sugar refineries, in Duisburg and later in Halle. During this phase of his career he was granted the title of professor in 1901. In 1904, Lippmann founded the Berlin Sugar Museum, still open today. From 1926–1933, he taught as a volunteer at Martin Luther University in Halle. In 1935, under the new Nazi regime he was stripped of the authority to teach because of his Jewish ancestry. In 1878 Lippmann published his first edition of what would become a reference monograph on sugar chemistry in his time. The 3rd edition of this work, published in 1904 in two volumes was 2000 pages long and attempted to cover every aspect of what had become a vast field. A contemporary review in Science noted that "With a modesty as charming as it is rare, he states in his preface: 'Completeness could not be attained in any direction', and yet this work is the most thorough of all works ever published on the chemistry of sugars", concluding that it was "rivaled by few, excelled by none". In 1890 Lippmann wrote an extremely detailed and influential history of sugar processing, Geschichte des Zuckers: seiner Darstellung und Verwendung, seit den ältesten Zeiten bis zum Beginn der Rübenzucker Fabrikation. To make it more accessible, he wrote an abridged version in 1894, which was also translated in French. In 1929 he published an updated version of his initial volume. Although an influential work in its day, 21st century scholars found it to be misleading with respect tosugar production in the Middle Ages. Lippmann also wrote extensively on the history of alchemy, from the perspective of it being a forerunner of chemistry rather than more philosophical considerations. His three-volume Entstehung und Ausbreitung der Alchemie is considered to contain the most detailed account of Greek alchemy, superseding earlier accounts of Marcellin Berthelot and C. Ruelle in accuracy. In 1920, George Sarton wrote in his review of the first volume that it was a "truly monumental work, the greatest single addition to our knowledge of ancient chemistry since the days of Kopp". In a review of the 1931 volume, Sarton warned that the portion dealing with Arabic materials was of lesser quality than the rest, particularly with respect to spelling of Arabic names. Yet more recent reevaluations point to some deficiencies in citation style that make the text difficult to follow back to primary sources. More compact accounts have been written since.