The Museum was founded in 1984 by comic art enthusiasts, with its primary founder being Malcolm Whyte, the publisher of Troubador Press. CAM's first incarnation had no fixed location, instead organizing showings at other local museums and corporate spaces. In 1987, with the help of an endowment from cartoonist Charles Schulz, it established a home on the second floor of the San Francisco Call-Bulletin Building in the South of Market area. In late 1994 the museum temporarily closed while it moved locations again; re-opening in the summer of 1995. Primary founder Malcolm Whyte retired from the museum's board of directors around the same time. In 1997, the museum suffered through serious financial difficulties, and was almost forced to close—this was despite a new endowment fund from the Schulz Foundation. Jenny E. Robb served as curator of the Cartoon Art Museum from 2000–2005. Current curator Andrew Farago took over from Robb in 2005. In 2001, the museum moved to a ground-floor location at 655 Mission Street in SoMa, which had been vacated by the Friends of Photography Ansel Adams Center. It closed the location in mid-September 2015 after the lease expired; the owners more than doubled the rent. In late 2016, the museum signed a 10-year lease on a historic, 8,000-square-foot brick building a block away from Ghiradelli Square. Almost a year later, during late October 2017, the Cartoon Art Museum finally reopened its doors at its new location with three new exhibitions, including a retrospective of the San Francisco cartoonist Raina Telgemeier, a tribute exhibition of Mike Mignola's Hellboy, and the emerging artist showcase featuring Nidhi Chanani.
Sparky Award
Over the years, the Museum has presented the Sparky Award, in honor of the lifetime achievement of prominent creators in the fields of cartooning and animation who "embody the talent, innovation and humanity of Schulz." The award, which is co-sponsored by the Charles M. Schulz Museum, includes a statuette of Snoopy holding a pen and leaning on an inkwell. The award debuted in 1998, and multiple winners were announced each year until 2001. After a six-year hiatus, the award was again presented in 2007. The most recent Sparky Award was given in 2015. The Sparky Award has been presented at various venues, including the San Diego Comic-Con and the New York Comic Con. List of Sparky Award winners:
The Museum hosts nine to 12 major exhibitions annually, along with classes for children and adults. It also offers lectures and operates a research library, a classroom and a bookstore.