CCL24
Chemokine ligand 24 also known as myeloid progenitor inhibitory factor 2 or eosinophil chemotactic protein 2 is a protein that in humans is encoded by the CCL24 gene. This gene is located on human chromosome 7.Function
CCL24 is a small cytokine belonging to the CC chemokine family. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. This chemokine is also strongly chemotactic for resting T lymphocytes and slightly chemotactic for neutrophils.Clinical significance
Elevated levels of eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease, such as asthma. People with lower plasma levels of eotaxin-2 have not been showing tendency to develop aspirin inducible asthma.
