Billboard Year-End Hot 100 singles of 2001
This is a list of Billboard magazine's Top Hot 100 songs of 2001.
| No. | Title | Artist |
| 1 | "Hanging by a Moment" | Lifehouse |
| 2 | "Fallin'" | Alicia Keys |
| 3 | "All for You" | Janet Jackson |
| 4 | "Drops of Jupiter " | Train |
| 5 | "I'm Real " | Jennifer Lopez featuring Ja Rule |
| 6 | "If You're Gone" | Matchbox Twenty |
| 7 | "Let Me Blow Ya Mind" | Eve featuring Gwen Stefani |
| 8 | "Thank You" | Dido |
| 9 | "Again" | Lenny Kravitz |
| 10 | "Independent Women" | Destiny's Child |
| 11 | "Hit 'Em Up Style " | Blu Cantrell |
| 12 | "It Wasn't Me" | Shaggy featuring Rikrok |
| 13 | "Stutter" | Joe featuring Mystikal |
| 14 | "It's Been Awhile" | Staind |
| 15 | "U Remind Me" | Usher |
| 16 | "Where the Party At" | Jagged Edge featuring Nelly |
| 17 | "Angel" | Shaggy featuring Rayvon |
| 18 | "Ride wit Me" | Nelly featuring City Spud |
| 19 | "Follow Me" | Uncle Kracker |
| 20 | "Peaches & Cream" | 112 |
| 21 | "Drive" | Incubus |
| 22 | "What Would You Do?" | City High |
| 23 | "Survivor" | Destiny's Child |
| 24 | "Lady Marmalade" | Christina Aguilera, Lil' Kim, Mýa and Pink |
| 25 | "Ms. Jackson" | OutKast |
| 26 | "Love Don't Cost a Thing" | Jennifer Lopez |
| 27 | "The Way You Love Me" | Faith Hill |
| 28 | "He Loves U Not" | Dream |
| 29 | "Butterfly" | Crazy Town |
| 30 | "Put It on Me" | Ja Rule featuring Lil' Mo and Vita |
| 31 | "Family Affair" | Mary J. Blige |
| 32 | "I Hope You Dance" | Lee Ann Womack |
| 33 | "South Side" | Moby featuring Gwen Stefani |
| 34 | "Don't Tell Me" | Madonna |
| 35 | "Get Ur Freak On" | Missy Elliott |
| 36 | "Crazy" | K-Ci & JoJo |
| 37 | "Fill Me In" | Craig David |
| 38 | "Someone to Call My Lover" | Janet Jackson |
| 39 | "With Arms Wide Open" | Creed |
| 40 | "Case of the Ex" | Mýa |
| 41 | "All or Nothing" | O-Town |
| 42 | "Bootylicious" | Destiny's Child |
| 43 | "I'm Like a Bird" | Nelly Furtado |
| 44 | "Kryptonite" | 3 Doors Down |
| 45 | "Fiesta" | R. Kelly featuring Jay-Z |
| 46 | "When It's Over" | Sugar Ray |
| 47 | "Jaded" | Aerosmith |
| 48 | "Promise" | Jagged Edge |
| 49 | "Missing You" | Case |
| 50 | "Differences" | Ginuwine |
| 51 | "This I Promise You" | 'N Sync |
| 52 | "Izzo " | Jay-Z |
| 53 | "Superwoman Pt. II" | Lil' Mo featuring Fabolous |
| 54 | "Crazy for This Girl" | Evan and Jaron |
| 55 | "Nobody Wants to Be Lonely" | Ricky Martin and Christina Aguilera |
| 56 | "I Just Wanna Love U " | Jay-Z |
| 57 | "One Minute Man" | Missy Elliott featuring Ludacris |
| 58 | "Danger " | Mystikal featuring Nivea |
| 59 | "Only Time" | Enya |
| 60 | "I Do!!" | Toya |
| 61 | "Never Had a Dream Come True" | S Club 7 |
| 62 | "Stranger in My House" | Tamia |
| 63 | "Irresistible" | Jessica Simpson |
| 64 | "Heard It All Before" | Sunshine Anderson |
| 65 | "The Space Between" | Dave Matthews Band |
| 66 | "There You'll Be" | Faith Hill |
| 67 | "Love" | Musiq Soulchild |
| 68 | "It's Over Now" | 112 |
| 69 | "No More " | 3LW |
| 70 | "Turn Off the Light" | Nelly Furtado |
| 71 | "Ain't Nothing 'bout You" | Brooks & Dunn |
| 72 | "Play" | Jennifer Lopez |
| 73 | "I'm Already There" | Lonestar |
| 74 | "My Baby" | Lil' Romeo |
| 75 | "Beautiful Day" | U2 |
| 76 | "Austin" | Blake Shelton |
| 77 | "Southern Hospitality" | Ludacris |
| 78 | "Grown Men Don't Cry" | Tim McGraw |
| 79 | "Livin' It Up" | Ja Rule featuring Case |
| 80 | "Loverboy" | Mariah Carey featuring Cameo |
| 81 | "Contagious" | The Isley Brothers featuring R. Kelly and Chanté Moore |
| 82 | "Who I Am" | Jessica Andrews |
| 83 | "Music" | Erick Sermon featuring Marvin Gaye |
| 84 | "I Wanna Be Bad" | Willa Ford |
| 85 | "Don't Happen Twice" | Kenny Chesney |
| 86 | "One More Day" | Diamond Rio |
| 87 | "I Wish" | R. Kelly |
| 88 | "It's a Great Day to Be Alive" | Travis Tritt |
| 89 | "I'm a Thug" | Trick Daddy |
| 90 | "Here's to the Night" | Eve 6 |
| 91 | "You Shouldn't Kiss Me Like This" | Toby Keith |
| 92 | "Get Over Yourself" | Eden's Crush |
| 93 | "Dance with Me" | Debelah Morgan |
| 94 | "So Fresh So Clean" | Outkast |
| 95 | "E.I." | Nelly |
| 96 | "Be Like That" | 3 Doors Down |
| 97 | "Most Girls" | Pink |
| 98 | "Oochie Wally" | Nas and Bravehearts |
| 99 | "Hero" | Enrique Iglesias |
| 100 | "Hemorrhage " | Fuel |