Andrej Šali


Andrej Šali is a computational structural biologist. Since 2003, he has been Professor in the Department of Bioengineering and Therapeutic Sciences at University of California, San Francisco. He also serves as an editor of the journal Structure.

Education

Šali received his Bachelor of Science degree in Chemistry from University of Ljubljana, 1987; his Ph.D. in Molecular Biophysics from Birkbeck College, University of London, 1991 ; and did postdoctoral work at Harvard University.

Research

Sali joined the faculty of the Rockefeller University in 1995, following his postdoctoral research at Harvard University. He is using computation grounded in the laws of physics and evolution to study the structure and function of proteins. For example, he developed comparative protein structure modeling by satisfaction of spatial restraints, implemented in program MODELLER and integrative structure determination of macromolecular assemblies, implemented in program IMP.

Research impact

Sali contributes greatly to structural biology by developing and applying computational methods for structural modeling and analysis of proteins. The two most often used programs developed by his research group include for comparative protein structure modeling and for integrative structure determination.
As of June 2017, Šali published approximately 370 papers, which were cited approximately 56,000 times per Google Scholar. His Hirsch-index is 104.
In 2018, Šali was elected member of the National Academy of Sciences in recognition of his contributions to biophysics and computational biology.

Notable alumni from Šali Lab