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5-HT1F receptor
5-hydroxytryptamine
receptor
1F
, also known as
HTR1F
is a
5-HT
1
receptor protein
and also denotes the
human gene
encoding
it.
Agonists
5-
n
-Butyryloxy-DMT: >60-fold
selectivity
versus
5-HT
1E
receptor
BRL-54443
-
mixed
5-HT
1E/1F
agonist
Eletriptan
- mixed 5-HT
1B/1D/1E/1F/2B/7
agonist
LY-334,370
- as well as related
benzamides
LY-344,864 -3-
Naratriptan
- mixed 5-HT
1B/1D/1F
agonist
Lasmiditan
-
selective
5-HT
1F
agonist, a first-in-class
ditan
molecule
Antagonists
MLS000756415