353 BC

By place

Persian Empire

• Mausolus, King and Persian satrap of Caria, dies and is succeeded in 352 BC by Artemisia, his sister and wife.

  Greece

• The Phocians threaten Thessaly to their north. Philip II of Macedon sees his opportunity to penetrate south.
• Clearchus, the tyrant of Heraclea, a Greek city on the Black Sea, is murdered by some of the city's citizens led by Chion after a reign of twelve years. Most of the conspirators are killed by the tyrant's body-guards upon the spot, while others are captured and put to death. Within a short time, the city falls under the rule of the new tyrant Satyrus, Clearchus' brother.