| Game | Date | Opponent | Venue | Result | Attendance | Goal Scorers |
| 1 | 7 August 2010 | Bradford City | Greenhous Meadow | 3-1 | 6,993 | Robinson Hat Trick '32 '51 '55 |
| 2 | 14 August 2010 | Macclesfield | Moss Rose | 1-0 | 2,302 | Harrold '3 |
| 3 | 21 August 2010 | Aldershot | Greenhous Meadow | 1-1 | 5,353 | Sharps '29 |
| 4 | 28 August 2010 | Stockport | Edgeley Park | 4-1 | 4,350 | Robinson '41, Harrold '58, Wright '63 '82 |
| 5 | 4 September 2010 | Rotherham | Greenhous Meadow | 1-0 | 6,206 | Ainsworth '5 |
| 6 | 11 September 2010 | Gillingham | Priestfield Stadium | 0-2 | 4,815 | |
| 7 | 18 September 2010 | Northampton Town | Greenhous Meadow | 3-1 | 5,527 | Harrold '12 Robinson '49 '53 |
| 8 | 25 September 2010 | Wycombe | Adams Park | 2-2 | 4,208 | Bradshaw '76 Ainsworth '87 |
| 9 | 28 September 2010 | Port Vale | Vale Park | 0-1 | 8,443 | |
| 10 | 2 October 2010 | Torquay | Greenhous Meadow | 1-1 | 6,034 | Robinson '5 |
| 11 | 9 October 2010 | Morecambe | Globe Arena | 0-1 | 3,239 | |
| 12 | 16 October 2010 | Lincoln City | Greenhous Meadow | 2-0 | 5,453 | Wright '39 Robinson '42 |
| 13 | 23 October 2010 | Chesterfield | B2net Stadium | 3-4 | 7,777 | Wright '80 McIntyre '89 Disley '90+3 |
| 14 | 30 October 2010 | Barnet | Greenhous Meadow | 2-1 | 5,331 | Disley '39 Harrold '41 |
| 15 | 2 November 2010 | Crewe Alex | Alexandra Stadium | 2-1 | 4,594 | Wright '5 '90+3 |
| 16 | 13 November 2010 | Stevenage | Broadhall Way | 1-1 | 2,765 | Harrold '55 |
| 17 | 20 November 2010 | Southend | Greenhous Meadow | 1-1 | 5,406 | Wright '49 |
| 18 | 23 November 2010 | Hereford | Greenhous Meadow | 4-0 | 6,565 | Wright Hat Trick '14 '64 '77 Cansdell-Sherriff '72 |
| 19 | 11 December 2010 | Cheltenham | Greenhous Meadow | 1-1 | 4,901 | Bradshaw '89 |
| 20 | 1 January 2011 | Burton | Pirelli Stadium | 0-0 | 3,594 | |
| 21 | 3 January 2011 | Crewe Alex | Greenhous Meadow | 0-1 | 6,561 | |
| 22 | 8 January 2011 | Morecambe | Greenhous Meadow | 1-3 | 4,605 | Cansdell-Sherriff '67 |
| 23 | 15 January 2011 | Barnet | Underhill Stadium | 1-1 | 2,164 | Hughes '27 o.g. |
| 24 | 18 January 2011 | Accrington Stanley | Crown Ground | 3-1 | 1,362 | Collins '50, '71, Wright '83 |
| 25 | 22 January 2011 | Chesterfield | Greenhous Meadow | 0-0 | 6,483 | |
| 26 | 25 January 2011 | Oxford United | Kassam Stadium | 1-3 | 6,264 | Wright '26 |
| 27 | 28 January 2011 | Bury | Gigg Lane | 0-1 | | |
| 28 | 1 February 2011 | Burton Albion | Greenhous Meadow | 3-0 | 4,343 | J. Taylor '55, '70, Harrold '72 |
| 29 | 5 February 2011 | Southend United | Roots Hall | 2-0 | 5,396 | J. Taylor 43', Harrold 60' |
| 30 | 8 February 2011 | Lincoln City | Sincil Bank | 5-1 | 3,202 | J. Taylor 6', Kelly 13', Ainsworth 22', 24', 35' |
| 31 | 12 February 2011 | Stevenage | Greenhous Meadow | 1-0 | 5,261 | Wroe 38' |
