1-deoxy-D-xylulose-5-phosphate synthase
In enzymology, a 1-deoxy--xylulose-5-phosphate synthase is an enzyme in the non-mevalonate pathway that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are pyruvate and -glyceraldehyde 3-phosphate, whereas its two products are 1-deoxy--xylulose 5-phosphate and CO2.
This enzyme belongs to the family of transferases, specifically those transferring aldehyde or ketonic groups. The systematic name of this enzyme class is pyruvate:-glyceraldehyde-3-phosphate acetaldehydetransferase . Other names in common use include 1-deoxy--xylulose-5-phosphate pyruvate-lyase , and DXP-synthase. This enzyme participates in biosynthesis of steroids.As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.
